On Computing the Coalescence Time Density in an Isolation-With-Migration Model With Few Samples

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On computing the coalescence time density in an isolation-with-migration model with few samples.

where f(t |Θ) is the probability density of the coalescent time. Assuming free recombination between loci, the full likelihood is a product of each locus likelihood. In order to determine the likelihood we must determine the density f(t |Θ) for coalescent of two samples in the IM model. Wang and Hey (2009) find the time to the MRCA by explicitly integrating over all possible sample paths in the...

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ژورنال

عنوان ژورنال: Genetics

سال: 2011

ISSN: 1943-2631

DOI: 10.1534/genetics.110.124164